TY - JOUR UR - https://doi.org/10.25259/VJIM_16_2021 DO - 10.25259/VJIM_16_2021 TI - An Interesting Case of Proteinuria: AL Amyloidosis AU - Chand,Dipti AU - Gosavi,Rajesh AU - Chakraborty,Anubhav AU - Kungar,Tejas AU - Paliwal,Yash AB - Light-chain (AL) amyloidosis is the most common form of systemic amyloidosis and is associated with an underlying plasma cell dyscrasia. The disease often is difficult to recognise because of its broad range of manifestations and what often are vague symptoms. The clinical syndromes at presentation include nephrotic-range proteinuria with or without renal dysfunction, hepatomegaly, congestive heart failure and autonomic or sensory neuropathy. Recent diagnostic and prognostic advances include the serum free light-chain assay, cardiac magnetic resonance imaging and serologic cardiac biomarkers. Treatment strategies that have evolved during the past decade are prolonging survival and preserving organ function in patients with this disease. This review outlines approaches to diagnosis, assessment of disease severity and treatment of AL amyloidosis. We describe a case of a 54--year-old male patient with monoclonal gammopathy with AL amyloidosis. VL - 32 T2 - Vidarbha Journal of Internal Medicine JO - Vidarbha Journal of Internal Medicine J2 - Vidarbha Journal of Internal Medicine SN - 0976-4356 ER -